An Independent Public RecordWednesday, June 17, 2026

MACEOPEDIA


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Subjects

COVID & Vaccines

Mace's public positions on COVID-19 mask mandates, vaccine policy, and natural immunity, including statements that shifted as the political environment changed.

Mace calling out Speaker Pelosi's reinstatement of the Capitol mask mandate, 2021. (Source: Rep. Mace's official "Interviews with Nancy," via YouTube.)

During the COVID-19 pandemic, Nancy Mace took a vocal libertarian-leaning stance on both mask mandates and vaccine policy. In July 2021 she framed Speaker Pelosi's reinstatement of indoor mask requirements in the Capitol as a "power grab" and publicly refused to comply, while also describing herself as a "proponent of vaccinations" in a November 2021 CNN interview, a position she said was grounded in personal responsibility rather than government coercion.

Also in November 2021, Mace argued on social media that natural immunity was "27 times" more effective than vaccination, citing a then-contested study. Public health officials disputed the figure at the time; the study itself was later criticized for methodological limitations. Mace did not retract the claim.

Her overall posture on COVID placed her in the camp of Republican members who resisted institutional public-health guidance while stopping short of outright vaccine rejection. The dispatches under this topic collect her public statements on the pandemic as she made them.